I could not even think about doing the drive from Bishkek to Osh, stay the night, then hire another car to the border of Uzbekistan and another on the opposite side to Tashkent. I felt like I had been on far too many rides, haggling and being cheated or worrying about what some jerk keeps in his car door or worse passenger door to make it look like it is ours or who decides to throw stuff through the window at night.